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For a lab manager, the distinction is similar to the difference between a screening reagent and a licensed reference standard

Research Evidence Comparison# Retatrutide Research# Phase 1 : First-in-human study established safety and pharmacokinetics Phase 2 (n=338) : Published in NEJM (2023), demonstrated dose-dependent weight loss up to 24.2% at 48 weeks with 12 mg dose

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In some situations, slowing down the infusion may be adequate to stabilize the patient and continue medication administration