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Upon mechanical or biochemical stimulation, resident cardiac fibroblasts become activated and differentiate into -smooth muscle actin (SMA)-expressing myofibroblasts, which are critical in the exacerbated secretion of ECM [2, 3]
Globally, affordability remains a concern
Lyophilized (unreconstituted) tirzepatide should be stored at controlled room temperature or refrigerated, depending on the manufacturer instructions
If we do not address those underlying shifts, weight loss becomes an uphill battle
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