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These modifications are critical because they protect the peptide from DPP-4 enzymesthe bodys natural "molecular scissors" that usually break down gut hormones within minutes
, What GLP-1 and GLP-1/GIP Medications Do for Inflammation 1) They Reduce Chronic Metabolic Inflammation Obesity and insulin resistance are associated with persistent, low-grade metabolic inflammation driven by visceral adiposity, oxidative stress, and hyperglycemia
doi: 10.1111/hex.13737, 28
In clinical trials, patients on tirzepatide 15mg lost an average of 20.2% of body weight at 72 weeks
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