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Several basic molecular and cellular mechanisms are shared among brain diseases, such as neuroinflammation, oxidative stress, excitotoxicity, neurodegeneration, disorders of neurogenesis, dysfunction of neurotrophic factor systems, which are most prominent in specific brain structures associated with different brain diseases [104, 105]

Understanding atherosclerosis as a chronic inflammatory disease offers new opportunities for the prevention and treatment of CAD

The breadth of the pipeline is genuinely good news, but the bottleneck moves rather than disappears