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Contraindications include: pregnancy and lactation, personal or family history of medullary thyroid carcinoma, Multiple Endocrine Neoplasia syndrome type 2 (MEN-2), history of pancreatitis, type 1 diabetes, severe gastrointestinal disease (including gastroparesis), and known hypersensitivity to GLP-1 analogues

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To quench the TMT-labeling reaction, 4 l of 5% hydroxylamine was added to each sample, followed by a 15-min incubation at room temperature with shaking