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FSEN1 was identified as a small-molecule inhibitor of FSP1 through chemical screening 118 , and subsequent structural analyses revealed that FSEN1 occupies the substrate-binding pocket of FSP1 in a position analogous to CoQ observed in the enzyme active site, providing structural insight into inhibitor recognition 119
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Melone MAB, Valentino A, Margarucci S, Galderisi U, Giordano A, Peluso G
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