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Therefore, we found that the enhanced insulinotropic effect of exendin-phe1 in vitro is recapitulated in a mouse model of T2D, suggesting that GLP-1R trafficking plays a role in determining the responses to therapeutic GLP-1R agonists in vivo
Using these different approaches of lipid estimation, we found that the three sterile mutants accumulated significantly more lipids than WT, particularly TAGs at day 1 of adulthood (Fig
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