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Guidelines from anesthesia and surgical societies recommend holding the weekly formulations of these drugs for at least a week before surgery, so careful planning is required if a patient is using these therapies

Moreover, other specialized mitochondria-residing proteins, such as the apoptosis inducing factor (AIF) and endonuclease G, are translocated to the nuclei following their release from mitochondria and promote peripheral chromatin condensation and high molecular weight DNA fragmentation

10.2174/1381612824666180608101119 61 SikiricP.SeiwerthS.GrabarevicZ.RucmanR.PetekM.JagicV.et al (1997)