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When skin laxity is extensive, a traditional approach may not achieve the desired level of tightening
Orlistat has important drug interactions, including with ciclosporin (avoid or monitor closely if unavoidable), warfarin (monitor INR), levothyroxine (separate by at least 4 hours and monitor TSH), antiepileptics (monitor for changes in seizure frequency), and acarbose (avoid combination)
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