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Structural and pharmacological characterization of novel potent and selective monoclonal antibody antagonists of glucose-dependent insulinotropic polypeptide receptor
Eleven brands across six molecules, made almost entirely by two companies Novo Nordisk and Eli Lilly: Semaglutide (Novo Nordisk) Ozempic, Wegovy, Rybelsus Tirzepatide (Eli Lilly) Mounjaro, Zepbound Liraglutide (Novo Nordisk) Victoza, Saxenda Dulaglutide (Eli Lilly) Trulicity Exenatide (AstraZeneca) Byetta, Bydureon BCise Lixisenatide (Sanofi) Adlyxin, no longer marketed in the US For weight management , the FDA has approved Wegovy, Zepbound and Saxenda
Excessive weight gain is associated with an increased risk of developing life-threatening comorbidities, such as hypertension or type 2 diabetes