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As a site where naive T lymphocytes develop, the thymus undergoes progressive age-related involution, characterized by stromal atrophy and adipose replacement, which diminishes T cell output and underlies immunosenescence in the elderly [363, 364]

However, individuals with kidney problems may struggle to excrete it, potentially leading to health complications

The honest answer: Retatrutide looks more powerful on headline weight-loss potential, but there is no true head-to-head trial against CagriSema yet