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Knocking out IL-23p19 reduces macrophage ferroptosis and improves the cardiac remodeling process [69] ( Fig
However, when senescent cells evade clearance and accumulate chronically, as often occurs with aging or in pathological conditions, their persistent SASP secretion becomes detrimental [55]
Each compound, diluted in 0.2 mL of phosphate-buffered saline (PBS), was administered via oral gavage, as shown in Supplementary Table 2
2022;28(7):gaac016
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