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Tissue depots (iWAT, iBAT, quadriceps muscle, liver) were excised, weighed, and frozen for further analysis
Co-ligand bonding and the trans effect
Interestingly, some authors suggest that obesity per se is not associated to increased sympathetic traffic to the muscle vasculature, but this alteration is present only when obesity is accompanied by OSAS (Narkiewicz et al., 1998)
It received US Food and Drug Administration (FDA) approval in 2014 for chronic weight management in adults with obesity or overweight and with at least one weight-related condition
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