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and promote blood vessel formation
In vitro angiogenesis assays demonstrate that GHK-Cu (0.1-1 M) increases endothelial cell tubule formation by 60-90% compared to untreated controls, with effects mediated through VEGF-independent pathways involving integrin receptor activation and focal adhesion kinase signaling
2022;15(727):eabo1118
Decades of research have revealed its role extends beyond sleep into stress adaptation, hypothalamic-pituitary regulation, and antioxidant pathways
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