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some respond strongly at lower doses, while others report minimal benefit
A recent meta-analysis of all the double-blind, placebo-controlled, randomized clinical trials of N-acetylcysteine as adjunctive therapy in bipolar depression confirmed its superiority over placebo in reducing depressive symptoms with a moderate effect size (95% confidence interval 0.060.84) [61]
Fu SC, Cheuk YC, Chiu WY, Yung SH, Rolf CG, Chan KM
In: Herrmann W, Obeid R, eds
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