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The studies are correlative, but appear to show that the drugs not only reverse the carcinogenic risks that come with obesity, they may also have additional anti-inflammatory effects that help suppress tumors

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The current standard operating procedure by the European Center for the Validation of Alternative Methods (ECVAM) recommends the use of MTT reduction as parameter to make prediction on the skin irritancy of substances using EpiSkin TM test method, while IL-1 endpoint is regarded as a useful adjunct to MTT assay 48