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Individual components are recognized nutrients, but that is not the same thing as an approved indication

[4] Kisspeptin-10 and Energy Metabolism Researchers posit that there may be a novel role of kisspeptin neurons as active players within the neuronal circuits that govern energy balance [...], offering [data supportive] of a bidirectional role of these neurons as a nexus between metabolism and reproduction. [5] Indeed, Kisspeptin-10 interacts with hypothalamic cells, and the hypothalamus is thought to be a brain region involved in the regulation of hunger hormone signals

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COA included