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These authors concluded that there is an increase in eryptosis levels with progressive residual diuresis and rGFR loss, probably due to decreased uremic toxins [268]

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Nausea, vomiting, and diarrhoea can lead to fluid and electrolyte losses, reducing circulating blood volume and causing orthostatic hypotension (a drop in blood pressure upon standing)

Overall, GLP-1 receptor agonists appear most beneficial for cardiometabolic risk reduction, obesity management, and prevention of atherosclerotic cardiovascular events