glp-1 drugs cancer The science around and is suddenly getting a lot more interesting GLP-1s: Weight Loss and Survival

A 2021 study identified a putative beta-arrestin "superagonist" of the ghrelin receptor, showing that biased agonism at this receptor could produce functionally distinct outcomes depending on which signaling pathway is preferentially activated

For individuals with severe or complex obesity (higher BMI and significant health issues), bariatric surgery is often considered the more effective and durable treatment, especially for long-term weight maintenance and disease remission

While SGLT2 inhibitors are clinically very important for heart and kidney health, the dramatic weight loss results of GLP-1s have made them a much bigger topic of conversation

doi: 10.1016/j.cmet.2017.07.011 77 DayJWOttawayNPattersonJTGelfanovVSmileyDGiddaJet al