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160 Moreover, intermittent fasting improved cognitive dysfunction in db/db mice by reconstructing the gut microbiota and altering microbial metabolites, likely via increased mitochondrial biogenesis and energy metabolism in the hippocampus

Currently, several senolytics were reported to kill senescent cells ( In this study, we tested the hypothesis that FOXO4-DRI treatment can selectively remove senescent cells in expanded human chondrocytes, thus enhancing their potential to generate high-quality cartilage

Serves as a nucleophilic co-substrate to glutathione transferases in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides

Herbal Options : Supplements like burdock root or turmeric may help overall detoxification efforts