[Ref] Renal Common (1% to 10%): Kidney failure (chronic hemodialysis patients) [Ref] Endocrine Common (1% to 10%): Parathyroid disorder [Ref] Respiratory Very common (10% or more): Pharyngitis (27%), cough increase (18%), dyspnea (11%), rhinitis (11%) Common (1% to 10%): Bronchitis, sinusitis [Ref] Dermatologic Common (1% to 10%): Pruritus, rash [Ref] Ocular Common (1% to 10%): Amblyopia, eye disorder [Ref] Genitourinary Common (1% to 10%): Urinary tract infection [Ref] Cardiovascular Very common (10% or more): Hypertension (21%), hypotension (19%) Common (1% to 10%): Atrial fibrillation, arrhythmia, cardiovascular disorder, electrocardiogram abnormal, palpitations, tachycardia, vascular disorder [Ref] Hypersensitivity Common (1% to 10%): Allergic reaction [Ref] Psychiatric Common (1% to 10%): Depression, anxiety, drug dependence, insomnia [Ref] Immunologic Very common (10% or more): Infection (24%) [Ref] References 1

These findings suggest a potential protective role for GLP-1 signaling in modulating orbital inflammation, though prospective trials are required for confirmation
The GLP-1 elevations observed with allulose consumption are generally small and transient compared to those achieved with pharmaceutical GLP-1 receptor agonists such as semaglutide or liraglutide, which produce sustained and pharmacologically significant increases in GLP-1 activity
[5] No shared excretion pathway exists