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Body composition changes require 3 to 6 months
Animals were housed according to IACUC guidelines in ventilated caging in a specific pathogen free animal facility
Allergic reactions or severe skin irritation should not be handled as routine monitoring
Ethacraplatin a dual-threat platinum (IV) prodrug is a cisplatin molecule coordinated to two ethacrynic acid ligands which is able to inhibit irreversibly GSTP1-1 enzymatic activity being reduced and cleaved as a consequence of binding (Fig
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