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J Pediatr.Gastroenterol.Nutr

Safety and Tolerability: What to Expect Both medications share similar side effect profiles, primarily gastrointestinal in nature: Nausea (typically most common) Diarrhea or constipation Decreased appetite Occasional vomiting Research indicates that the incidence of gastrointestinal side effects is comparable between the two medications

Youve run into a weight loss plateau If youve been taking Zepbound for a while and losing weight pretty consistently, but now it seems to have stopped working, its possible youve hit a weight loss plateau

Additional research also suggests that adverse GI side effects may be to blame for the high discontinuation rates of medicines such as Ozempic