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For example, rat TDSCs treated with IGF-1 (1, 10, and 100 ng/mL) for 28 days exhibited the increased expression of tendon-specific marker (SCX) and significantly decreased expression of chondrogenic and osteogenic marker (collagen type II) (Holladay et al., 2016)
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For a condition that affects roughly 30% of the global population and has limited treatment options, these results are extraordinary
S., & Moseley, L
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