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Although the mechanism of action of BPC157 remains unclear, BPC157 has demonstrated significant effects at very low doses with very good stability (Sikiric et al., 2018)
Additionally, the relatively short duration of our study (12 weeks) may not have been sufficient to detect changes in this parameter
Synovial inflammation is associated with pain sensitization in patients with knee OA 46 , suggesting a role of pro-inflammatory mediators in this process 39
The peptide appears to work through multiple mechanisms: direct anti-inflammatory effects, improved tissue healing, and enhanced blood flow to damaged areas
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