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The diagnosis of ALS is primarily a clinical one and requires the appearance of both upper (increased tone and reflexes) and lower (fasciculations and muscle atrophy) motor neuron involvement in many segments of the body
Peptides are sensitive molecules and vulnerable to degradation from a host of environmental species including but not limited to bacterial contamination
demonstrated that GLP-1 agonist administration could lead to an increase in neurogenesis in the hippocampus dentate gyrus region, and demonstrated an improvement in mood and cognitive function through the swim test in adult rodents (Isacson et al., 2011)
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