Recent clinical studies on these drugs seem to offer new hope for some conditions, such as age related macular degeneration and uveitis, they highlight, but with potential risks of severe, though rare, ocular complications, such as ION, for others. 10/03/2026 Notes for editors Short report: Ischemic optic neuropathy with semaglutide: global observational analysis of sex- and formulation- specific risk Doi:10.1136/bjo-2025-328483 Commentary: Effects of anti-obesity medications in the retina: a gathering storm or sunshine ahead
The resulting high demand for the drug and the inevitable drug shortages of this medication for persons with T2DM have resulted in stricter guidelines for authorized usage of this drug, as well as off-label usage
P = 0.004
Neurosci Biobehav Rev 37:28872899 Liu D, Li S, Gong L, Yang Y, Han Y, Xie M, Zhang C (2019) Suppression of microRNA-141 suppressed p53 to protect against neural apoptosis in epilepsy by SIRT1 expression