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August 2025 : The US FDA approved Wegovy (semaglutide 2.4 mg) for the treatment of noncirrhotic metabolic dysfunction-associated steatohepatitis (MASH) in adults with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis), in combination with a reduced-calorie diet and increased physical activity
Critically, a study has shown that the levels of GSH, a key antioxidant, are significantly reduced in the AD brain and that the extent of this depletion correlates positively with the severity of cognitive impairment (43)
2e, f), as in our first study (Fig
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