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A: Yes, modestly
For most first-time users, topical GHK-Cu at 1% to 2% can deliver visible results without the complexities associated with compounded injectables
Duloxetine's FDA label specifically warns that "blood pressure should be measured prior to initiating treatment and periodically measured throughout treatment" [4]
As a general rule, IM is favored when the goal is rapid correction of a clinical deficiency, when the patient has difficulty absorbing B12 through oral or sublingual routes, or when a provider wants predictable peak serum levels
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