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Individuals with DS over the age of 35 have a higher frequency of short-term memory impairment and an increase in the rate of dementia, aphasia, and agnosia, while executive function impairments are evident as early as adolescence

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Discontinuation, regain, and reinitiation (class-level, semaglutide / tirzepatide) Budini 2026 ( eClinicalMedicine ) pooled regain curve: asymptotic maximum regain 75.3% of lost weight, half-life about 23 weeks, so roughly 60% of the loss returns by 12 months and about 40% is still held at a year

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Molecular mechanisms of hepatic metastasis in colorectal cancer

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