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change from baseline to week 104 in body weight (in kg), BMI, HbA 1c , fasting plasma glucose, fasting serum insulin, diastolic blood pressure, lipids (total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, very-low-density lipoprotein cholesterol, free fatty acids and triglycerides) and C-reactive protein

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Semaglutide delays 4-hour gastric emptying in women with polycystic ovary syndrome and obesity, Diabetes, Obesity and Metabolism (2023) Wegovy (semaglutide) injection, Novo Nordisk (2024) Semaglutide (Wegovy): CADTH reimbursement review: Therapeutic area: Weight management, Canadian Agency for Drugs and Technologies in Health (2022) Assessment of water consumption during Ramadan intermittent fasting: Result from Indonesian cross-sectional study, Frontiers in Nutrition (2022) Soluble fiber, University of Michigan Health (2024) How to calculate how much water you should drink, University of Missouri (2022) Exercise therapy in patients with constipation: A systematic review and meta-analysis of randomized controlled trials, Scandinavian Journal of Gastroenterology (2019) Are Prunes Good for Constipation?, Mid-Atlantic Permanente Medical Group (2024) Psyllium, MedlinePlus (2024) Efficacy of probiotic compounds in relieving constipation and their colonization in gut microbiota, Molecules (2022) Semaglutide, StatPearls (2024) Constipation, StatPearls (2023) Treatment of chronic constipation: Prescription medications and surgical therapies, Gastroenterology and Hepatology (New York) (2015) Medically accurate: SingleCares Medical Review Board analyzes all of our content to confirm its in line with current medical advice

Carefully manage the use of diuretics and RAAS blockers (e.g., ACE inhibitors, ARBs)