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There are several other things we could unpack about GLP-1 RA medications, but the only other piece of information you need to know to understand why these natural GLP-1 alternatives are (very) misleading is: half-life

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Back Unger, RH, Eisentraut, AM, Madison et al (1959) 'Glucagon antibodies and their use for immunoassay for glucagon', Experimental Biology and Medicine , 102/3

15 likewise, lixisenatide was withdrawn from the US market as of January 1, 2023, for commercial reasons, rather than because of any safety or efficacy issues