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Who Saxenda Is Best For Saxenda may be especially useful for individuals who: Prefer a daily dose rather than a weekly injection Need a gentler appetite-regulating tool Have gastrointestinal side effects on higher potency weekly agents Have insurance plans that cover liraglutide but not semaglutide or tirzepatide Want a gradual, steady shift in appetite patterns rather than a rapid one Are early in their weight loss journey and want to build confidence before transitioning to other therapies Saxenda is also an option for patients preparing for bariatric surgery who require moderate appetite control, blood sugar stabilization, or weight reduction prior to the operation