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persistent vomiting or signs of dehydration
If the patient is dehydrated from hypovolemia, then fluid resuscitation may be indicated along with an antiemetic if nausea/vomiting are present
It does not approve a finished compounded drug product
ATTAIN-1 (NCT05869903) was a Phase III, 72-week, randomized, double-blind, placebo-controlled trial comparing the efficacy and safety of orforglipron at various doses to placebo in adults with obesity, or overweight with at least one of the following comorbidities: hypertension, dyslipidemia, obstructive sleep apnea or cardiovascular disease, who did not have diabetes
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