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Clinical trials (SURPASS and SURMOUNT programmes) did not identify hot flushes as a significant adverse event

Women accounted for 65% (n = 242) of the reports whereas men accounted for 29% (n = 108)

Clinical trials have highlighted significant weight reduction in participants without diabetes, with many experiencing a decrease in body weight ranging from 10% to 15% from their baseline over 68 weeks when combined with lifestyle modifications like diet and exercise

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