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In this absence of therapeutic advances, the proliferation of societal factors that promote weight gain has left the United States with a 41.9% prevalence of obesity and a 73.9% prevalence of overweight or obesity among its adult population, according to the National Center for Health Statistics
Patients with pernicious anaemia, malabsorption disorders (such as Crohn's disease or coeliac disease), or following gastric surgery require regular B12 supplementation to prevent serious complications including megaloblastic anaemia and neurological damage
These metabolites may have certain biological activity or no activity, and their subsequent fate and effects need further research
When the body experiences substantial caloric deficit and metabolic changes, it may prioritize essential functions over non-essential processes like hair growth
