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doi: 10.1111/j.1365-2125.2012.04214.x 33 PykeCHellerRSKirkRKrskovCReedtz-RungeSKaastrupPet al
The right cadence depends on factors such as: Health goals: Skin brightening protocols may require longer loading phases than general wellness support
Pigmentation effects accumulate over days to weeks of repeated administration, because melanogenesis is a slow process dependent on melanocyte turnover (4-6 weeks for a complete epidermal cycle)
We chose transcripts with fold-change values of greater than or less than 2 (upregulated and downregulated, respectively)
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