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In pill form, it supplements dietary magnesium for: Bone health Muscle function Blood sugar regulation Migraine prevention Heart health and blood pressure control Mechanism of action for constipation Acts as an osmotic (saline) laxative by: Relaxing bowel muscles Drawing water into the intestines Softening stool and increasing bowel movement frequency Common side effects Stomach pain or cramps Bloating and gas Nausea Diarrhea Serious side effects (rare) Allergic reaction (hives, facial or throat swelling, breathing difficulty) Irregular heartbeat Low blood pressure Muscle weakness Drowsiness or confusion Dizziness Dehydration and electrolyte imbalance Bloody stools or rectal bleeding Safety precautions Usually safe when used as directed

Moreover, decreased IGF-1R expression was observed in AngII/PE-infused hearts

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