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Combining AOD-9604 and 5-Amino-1MQ creates synergy through complementary metabolic pathways: AOD-9604 stimulates lipolysis via beta-3 adrenergic receptors to mobilise stored triglycerides, while 5-Amino-1MQ inhibits NNMT enzyme activity to restore NAD+ availability and mitochondrial oxidative capacity

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''It wasn't really having an effect, but also the cost was a factor because there were other ingredients in the formulation that from a fat-reduction perspective were more effective,'' says Phosphagenics' chief scientific officer, Paul Gavin