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Increased activity of the PPP promotes the survival and development of cancer cells in an acidic environment by mediating the AMP-activated protein kinase (AMPK)/ YAP/matrix metallopeptidase 1 (MMP1) signaling axis [48]
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A wave of drugs is currently in development to capture a market that is expected to be north of $100bn in size
Eur Heart J 44(39):40434140
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