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Individuals already taking GLP-1 receptor agonists for diabetes or weight management should continue their prescribed therapy as directed, but should not expect guaranteed cognitive benefits beyond those associated with improved metabolic health

By shrinking visceral fat depots, they reduce the inflammatory chatter that accelerates tissue damage, a phenomenon frequently referred to as inflammaging. And by easing the metabolic stress on blood vessels and organs, they likely reduce the buildup of dysfunctional, senescent cells that accumulate with age

F.HorngA.NiethammerT.PagenstertI.SieversB.JanssonV.et al (2009)

Those committee members who made the recommendations are practicing pharmacists, physicians and patient representatives whose hands-on, real-world experience and expertise complement the regulatory knowledge of FDA's career staff