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Epidemiological evidence demonstrates a strong association between obesity and KOA, highlighting shared pathogenic mechanisms
The gut-brain axis is a two-way communication system between your gut and your brain
Trials on stroke and traumatic brain injuries with competitive glutamate or glycine antagonists (i.e., selfotel, aptiganel, eliprodil, licostinel, and gavestinel) have failed (Pereira and Goudet, 2019)
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