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GSTs conjugate 4HNE to GSH, and the corresponding glutathionyl-4-HNE (GS-HNE) is actively transported out of cells via RLIP76, a multifunctional membrane transporter for GSH-conjugated compounds, and/or MRPs (multidrug-resistance proteins
pylori- infected gastric cells under certain conditions [53,54]
In fact, most clinicians emphasise continuing unless symptoms are severe or persistent
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