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Chen, PhD, PharmD, OMD, LAc Reviewed by Tina T
Long-term cardiovascular safety and efficacy of GLP-1 receptor agonists in high-risk cardiovascular populations: systematic review and meta-analysis (PMID 42063138)
In 2026, the Phase 3 SYNCHRONIZE-1 trial reported topline mean weight loss of about 16.6% at 76 weeks versus about 3.2% on placebo
Diarrhea usually occurs in the first one to three days after dose escalation and resolves within a week
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