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In cells , GLP-1(736) activates the GLP-1 receptor (GLP1R), which increases intracellular cAMP levels and subsequently activates PKA and CREB, leading to enhanced insulin secretion

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The incremental prognostic importance of body fat adjusted peak oxygen consumption in chronic heart failure

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4 Discussion In this review, we briefly introduced the natural sources, biosafety and bioactivity of lycopene and summarized its potential efficacy as well as mechanisms underlying its preventive effects on digestive premalignant lesions

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