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Eli Lilly is arguably winning the GLP-1 game right now
In September 2025, clinical research was published on weight loss for two oral incretin therapies: an oral version of semaglutide and Orforglipron, also a GLP-1 receptor agonist
B., Akbari, M., Kolahdooz, F., Esmaillzadeh, A., Nadi-Ravandi, S., Mazoochi, M., & Asemi, Z
Research supports a step-down approach where you reduce calories by 200-300 per week rather than making dramatic cuts
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