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Placental hypoxia or ischemia among preeclampsia patients is thought to be the cause of the formation of free radicals such as malondialdehyde (MDA), which decreases endogenous antioxidants such as glutathione (GSH)

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The researchers mixed AOD9604 with human blood serum and rat plasma in test tubes to simulate what happens after the peptide enters the body

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As for safety, gastrointestinal adverse events were generally mild and dose-related

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