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[9] Regulation [edit] Activation [edit] Receptors that activate this pathway are mainly G protein-coupled receptors coupled to the G q subunit, including: 5-HT 2 serotonergic receptors 1 (Alpha-1) adrenergic receptors [10] Calcitonin receptors H 1 histamine receptors Metabotropic glutamate receptors, Group I M 1 , M 3 , and M 5 muscarinic receptors Thyroid-Releasing Hormone receptor in anterior pituitary gland Other, minor, activators than G q are: MAP kinase

Wilheilm, K