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As the key enzyme responsible for clearing lipid peroxides [86], GPX4 undergoes site-specific palmitoylation at Cys75 and Cys66, which convey distinct molecular instructions related to localization and stability,, respectively, collectively determining whether cellular ferroptosis will occur

The two other proteins from Arabidopsis are predicted to be cytosolic as they do not exhibit visible targeting sequences

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Multiple organ failure including sepsis-induced cardiac dysfunction seem to be the result of numerous factors as overwhelming inflammation and nitric oxide synthesis impairment associated with mitochondrial dysfunction and increased oxidative stress (Cecchini and Cecchini, 2020)