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It activates both GLP-1 receptors and GIP (glucose-dependent insulinotropic polypeptide) receptors
The first meta-analysis in this field also provided the first attempt of data stratification into ethnic groups, and particularly the author performed a subgroup analysis in Caucasians, called whites in the original paper, including data from both European and North American studies and observing no significant contribution of the polymorphism in this group (Zintzaras, 2007)
Truncated IGF-1 variant with approximately 10x greater receptor affinity than IGF-1-LR3 due to reduced binding protein interaction
Pagliari, and M
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